Sh Hezarkhani, F Nik Nejad, N Shahini,
Volume 8, Issue 3 (Autumn[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Onychomycosis is a fungal nail infection causing ulcers, diabetic foot and enhance nail infection. This study was designed to evaluate the prevalence of onychomycosis in type II diabetes.
Material and methods: This descriptive-analytic study was conducted on 300 diabetic patients selected randomly among those referred to Panje Azar endocrinology clinic. They were examined for peripheral vascular disease, Skin lesions, diabetic foot and Peripheral neuropathy. The Laboratory tests such as FBS, HbA1c, Direct smear and fungal culture were used.
Results: The patients with onychomycosis were 19 (6.3%) their mean age was 53.65±1.04 the youngest was 28 and the oldest 84. The male to female infection ratio was of 1.08 that was not statistically significant. There was no significant difference in regards to ethnicity, age, BMI, FBS, HbA1C. The location of the infection was 16 on feet (29.6%), and three on both hands and feet (P = 0.000)
Conclusion: The prevalence of fungal infection was less frequent than that of other studies. Given that there was no significant relationship between different demographic data and its prevalence, further studies with larger sample size are needed.
Keywords: Prevalence, Fungal Infections, Diabetes
Dr Hamid Malekshahiniya, Dr Roohollah Mohammadi Mirzaei, Dr Halimeh Vahdatpoor,
Volume 19, Issue 1 (4-2025)
Abstract
The aim of this study is to investigate the effect of 6 weeks of intermittent exercise on the serum level of nitric oxide, insulin resistance and some lipid profiles in male diabetic rats. Materials and methods: In this experimental study, 60 anesthetized rats (200±20) were randomly divided into 6 groups of 10:1-control-healthy, 2-sham, 3-periodic, 4-periodic+saline, 5-diabetic and 6- Diabetes + interval training were divided. Diabetes was induced by intraperitoneal injection of nicotinamide-streptozotocin. The subjects trained on the treadmill for 6 weeks, 5 sessions a week. 48 hours after the last training session, slaughter was performed and then glucose, insulin, nitric oxide, LDL, HDL, TG and cholesterol levels were measured. One-way variance test and Tukey's post hoc test were used for data analysis(p<0.05). Results: Induction of diabetes increased glucose and insulin resistance and decreased insulin and nitric oxide in the diabetic group compared to the control group. After 6 weeks of intermittent training in the diabetes group + intermittent training, the amount of glucose and insulin resistance decreased compared to the diabetes group, but the nitric oxide level increased compared to the diabetes group. But it had no effect on insulin levels. Also, 6 weeks of intermittent training had no significant effect on the amount of lipid factors in different groups(p<0.05). Conclusion: According to the results of the present study, it seems that interval training can create a protective effect against vascular diseases in diabetic patients by reducing insulin resistance and increasing nitric oxide, and as a result, improving vascular function.
