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Reza Habibipour, Gholamreza Zarrini, Shohreh Yarizadeh,
Volume 11, Issue 3 (May-Jun 2017)
Abstract

ABSTRACT
       Background and Objective: Nanobacteria are nanometer-scale particles with different shapes, which have been a subject of debate in modern microbiology. They belong to a proposed class of living organisms, specifically cell-walled microorganisms with a size much smaller than the generally accepted lower limit for life. Since some microorganisms are able to continue growth at high temperatures, we aimed to isolate thermophilic bacteria from Gheinarcheh hot spring in Ardabil (Iran) and identify the characteristics of these microorganisms.
       Methods: Microbial mats were found in cultures from Gheinarcheh hot spring in North West of Iran. Synthetic media were prepared and used for isolation of protease-producing thermophilic bacteria, and identification of the features of microbial mats. Cultures were incubated at temperature range of 60-120 oC. Scanning electron microscopy, DNA extraction and polymerase chain reaction were used to further identify characteristics of the microbial biofilms.
        Results: Microbial biofilms of nanoparticles were detected in our samples. Growth of the bacteria increased at all temperatures tested. Results of scanning electron microscopy showed nano-sized particles in the scale of 60 nm. No band was visible in gel electrophoresis of polymerase chain reaction products.
Conclusion: This study is the first to report the presence of hyperthermophilic nanobacteria in Iran.
      Keywords: Nanobacteria, Hyperthermophile, Microbial Mat.

Marzeyeh Mirzazadeh Bakhteyari , Saied Shakerian, Mohsen Ghanbarzadeh,
Volume 15, Issue 3 (May-Jun 2021)
Abstract

Background and objectives: The prevalence of obesity and overweight in women is increasing. Secretion of adipokines such as vaspin may affect insulin sensitivity. It has been suggested that physical activity can alter circulating vaspin levels. The purpose of this study was to investigate effects of six weeks of aerobic interval training on serum vaspin and blood glucose levels in obese inactive girls.
Methods: In this quasi-experimental study, 22 inactive overweight girls were selected from the Shahid Chamran University of Ahvaz, Iran. The mean age, weight and body mass index of the subjects were 24.22±1.35 years, 83.77±12.66 kg and 32.56±3.36 kg/m2, respectively.  The subjects were randomly divided into an experimental group )n=11) and a control group )n=11). The experimental group performed aerobic training on stationary bicycle at 65-80% of maximal strength, three sessions a week for six weeks. Serum levels of vaspin and glucose were measured using commercial kits. Data were analyzed using SPSS (version 23) and at significance of 0.05.
Results: The training intervention had no significant impact on the serum vaspin and glucose concentrations (P>0.05). In addition, the covariance analysis showed that serum vaspin and glucose levels did not differ significantly between the study groups (P>0.05).  
Conclusion: Based on the results, the six-week aerobic interval training had no significant effect on vaspin and blood glucose levels of inactive obese girls. It is recommended to further examine the effect of this type of exercise at higher intensities and for longer durations.
Abazar Yari , Morteza Ahmadi , Mahdieh Mehrpouri ,
Volume 18, Issue 5 (Sep-Oct 2024)
Abstract

Background: Thyroid hormones play a critical role in hematopoiesis, and thyroid disorders such as hypothyroidism and hyperthyroidism can affect blood parameters. Therefore, this study aimed to evaluate the effect of thyroid dysfunction on various blood parameters.
Methods: This case-control study included 194 subjects who were classified into three groups based on TSH levels: hypothyroid (n=70), hyperthyroid (n=56), and control (n=68). Conditions that affect blood parameters, including pregnancy, inherited or acquired red blood cell abnormalities, chronic inflammatory diseases, evidence of nutritional deficiencies, and underlying diseases such as cancer, as well as patients unwilling to participate in the study, were excluded. Hematological parameters were measured using a cell counter, and the results were analyzed using SPSS software.
Results: The results showed that 78% of the participants were female and 22% were male, aged 4 to 89 years. The analyses revealed that RBC, Hb, HCT, WBC count, and WBC differential count were significantly different between the three groups (P-value <0.05), but the differences were not significant for MCV, MCH, MCHC, RDW, PLT, and MPV (P-value >0.05). Correlation analysis indicated a significant correlation between TSH and Hb, HCT, WBC, PLT, neutrophils, lymphocytes, monocytes, and eosinophils (P<0.05).
Conclusion: Since thyroid hormones play a critical role in hematopoiesis, thyroid dysfunction can affect many hematological parameters. Therefore, the management of patients with thyroid disease should include the CBC test. In addition, patients with poor responses to anemia treatment may have an underlying thyroid disorder.



Shalaleh Ganji, Iraj Mobedi, Azim Rezamand, Farshid Ardabili, Pooya Yari, Majid Khanmohammadi,
Volume 19, Issue 1 (4-2025)
Abstract

Background and objectives: Enterobius vermicularis is the most important intestinal parasite in children worldwide. When this parasite migrates unexpectedly, the larvae move out of the intestine and enter organs such as the appendix and can cause health risks.
Case report: An 8-year-old boy was admitted to the oncology clinic of Tabriz Children’s Hospital complaining of fever of 39-40°C with abdominal pain, cramps, loss of appetite, weakness and fatigue associated with cervical lymphadenopathy, hepatomegaly, axillary mass, abdominal upper thigh, maculopapular rashes and tiny petechiae on the chest and abdomen.
Results: On CT examination of the chest, moderate mediastinal and mesenteric lymphadenopathy was noted. The patient was hospitalized with a definitive diagnosis of acute lymphoblastic leukemia (ALL). On the seventh day of hospitalization, the patient developed additive colic pain (contraction and cramping) around the umbilicus and concomitantly developed pain downward and rightward into the abdomen. Based on the clinical findings, the patient was thought to have acute appendicitis. Pathological examinations showed that E. vermicularis was the cause of the appendicitis.
Conclusion: The results of this study indicate that this parasite may be associated with inflammation of the appendix in patients with acute lymphoblastic leukemia. A screening program is still required in patients with immunodeficiency or those taking immunosuppressive drugs.
 

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