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Showing 3 results for Alkaline Phosphatase
Effect of Different Concentrations of Lead Nitrate on Biochemical Parameters of Alfalfa
Reihaneh Sabbaghzadeh,
Volume 14, Issue 3 (5-2020)
Abstract
Background and objectives: Polyphenols can exert free radical scavenging effects by naturalizing dangerous reactive oxidants. Formation of reactive oxygen species can cause oxidative damage to human cells, leading to various diseases such as cancer, cardiovascular disease, osteoporosis and degenerative diseases. In this study, we investigated effect of treatment with various concentrations of lead (II) nitrate, a toxic and an oxidizing agent, on growth and biochemical parameters of alfalfa (Medicago sativa L.).
Methods: Total phenol content was estimated by the Folin-Ciocalteu method. The 1,1-diphenyl-2-picrylhydrazyl (DPPH) stable free radical was used for assessment of free radical-scavenging activity. Changes in the activity of catalase and peroxidase as well as in the level of proteins, phenol content and malondialdehyde (as marker of lipid peroxidation) were investigated following treatment with different concentrations (0, 8, 12 and 16 mg/l) of lead nitrate for 21 days. All experiments were done in triplicate. Butylated hydroxytoluene and quercetin were used as standard controls.
Results: Treatment with lead significantly altered the level of total phenolic content, proteins, malondialdehyde and the activity of catalase and peroxidase (P<0.05).
Conclusion: Our results indicate that lead-contaminated soil can significantly alter biochemical and growth parameters of alfalfa.

 
Effect of Four Weeks Plyometric Training with and without Blood Flow Restriction on Serum Bone Formation and Degeneration Markers in Inactive Girls
Fatemeh Fakhri, Abdolhamid Habibi, Mohsen Ghanbarzadeh, Rohollah Ranjbar,
Volume 14, Issue 3 (5-2020)
Abstract
Background and Objectives: It has been shown that low intensity physical activity rarely increases bone density or renewal. Therefore, the purpose of this study was to investigate effects of four weeks of plyometric training with and without vascular occlusion on serum levels of bone‌ alkaline phosphatase (BALP) and C-terminal telopeptide of type I collagen (CTX), as markers of bone formation and bone degeneration in inactive girls.
          Methods: This was a semi-experimental study with a pretest-posttest design. The study population consisted 36 inactive female students aged 23.84±1.096 years with a mean body mass index of 22.59±0.52 kg/m2 who were randomly divided into a plyometric training group without blood flow restriction, a plyometric training group with blood flow restriction and a control group. The experimental groups performed four weeks of plyometric training (three sessions per week), while the control group did not perform any exercise. Blood samples were obtained 48 hours before the first training session and 48 hours after the last training session. Measurement of BALP and CTX was carried out using commercial enzyme-linked immunosorbent assay kits. Collected data were analyzed using t-test and one-way analysis of variance. All statistical analyses were performed using SPSS software (version 23) and at significance level of ≤ 0.05.
          Results: The level of BALP was significantly higher in the low intensity exercise with blood flow restriction group compared to the control group (P=0.005) and the low intensity exercise group without blood flow restriction (P=0.003). The BALP/CTX ratio, as marker of bone metabolism, increased significantly following low intensity exercise with blood flow restriction compared with the other groups (P<0.05). However, low intensity exercise without blood flow restriction induced no significant change in the studied indices.
          Conclusion: Plyometric training with blood flow restriction could be as effective as high intensity training for improving bone metabolism and turnover, particularly in inactive individuals.

Comparison of the Levels of Bone Metabolic Markers between Young Female Basketball Players and Non-Athlete Females
Asra Askari, Bobysun Askari, Saqqa Farajtabar Behrestaq,
Volume 17, Issue 1 (1-2023)
Abstract
Background and objectives: Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue. It is the most common chronic metabolic bone disease. The purpose of this study was to compare the level of bone metabolic markers including parathyroid hormone (PTH), alkaline phosphatase (ALP), calcium, and phosphorus between female basketball players and non-athlete females.
Methods: Twelve female professional basketball players (aged 20-35 years) of the Super League of Golestan Province (Iran) were enrolled as the experimental group. Fifteen age-matched non-athlete females were also selected as the control group. Plasma levels of PTH, ALP, calcium, and phosphorus were compared between the study groups.
Results: The levels of PTH (p=0.004) and ALP (p=0.001) were significantly higher in the experimental group than in the control group. The levels of calcium and phosphorus did not differ significantly between the study groups (p>0.05).
Conclusion: Based on the results, it could be stated that performing weight-bearing sports activities such as basketball can improve the density of bone minerals and the factors stimulating bone formation.
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