Showing 5 results for Radiation
N Bahaedini, M Atefi, Mj Mortazavi,
Volume 2, Issue 2 (10-2008)
Abstract
Abstract Background and Objectives: Incidents related to electromagnetic interference with medical devices have been reported over the past decades. It has also been indicated that the microwave radiation emitted from mobile phones interferes with the operation of medical devices therefore, this study aimed at testing the interference by GSM mobile phones with cell counters. Material and Methods: We did this experimental Study on thirty-two heparinized blood samples of 32 healthy individuals Selected randomly. The Cell Counting was Carried out in the presence of Electro magnetic field produced by three Cell phones with different levels of SAR (Low, intermediate and High) and without being in electromagnetic field. Statistical tests were used to analyze the data (p<0.05). Results: Microwave radiation emitted from cell phones, regardless of their SAR, interferes with the proper operation of cell Counter. This interference leads to false Counting. Conclusion: As mobile phones emit microwave radiation in an isotropic manner, keeping mobile phones at a safe distance, 15cm, from medical equipments will be necessary. These observations confirm the need for some restrictions of mobile phone use in hospitals and medical laboratories. Key words: Interference, Cell Counters, Mobile Phone, Microwave Radiation
Noroozi , R, Mehdinezhad, Mh, Zafarzadeh A,
Volume 5, Issue 2 (10-2011)
Abstract
Abstract: Background and objectives: There is a great interest in photocatalytic oxidation of contaminants, using ZnO, in recent years. The main objective of this research was to study photocatalytic disinfection of E. coli bacteria as water microbial pollution index, using nano particles of ZnO and a UV lamp in a batch reactor. Material and Methods: In this study, the contaminated water sample was prepared through adding 102 and 103 E. coli bacteria per ml of raw water. The contaminated water entered the photocatalytic oxidation reactor and removal efficiency of E. coli bacteria in different conditions were studied, including pH (5.5, 7, and 9), time (10, 20, 30, 40, 50 and 60 mins), dose of nano particles ZnO (0.2,0.4,0.8 and 1 gr/l), number of bacterium (102 and 103 per milliliter) and voltage of UV-C lamp, 27 volts. Characterizations of ZnO nanoparticles were determined using scanning electron microscope equipped with Energy Dispersive X-ray Analysis (EDX) system and X-ray diffraction (XRD) method. Results: Photocatalytic process efficiency is enhanced by increasing reaction time and dose of nano particles ZnO in the presence of UV lamp irradiation. The results show that the best conditions for removal of 102 and 103 bacteria per milliliter are obtained from condition including pH of 7, reaction time of 30 mins, 0.8 gr/l doses of nano particles ZnO and 27-volt-UV lamp. Conclusion: The results indicate that the increase of reaction time and dose of nano particles ZnO, in the presence of radiation UV lamp, have the most significant effect on photocatalytic efficiency. Based on the results, photocatalytic can be promising method for removal of E. coli bacterium from drinking water. Keywords: Photocatalytic, E. coli, irradiation UV, ZnO nanoparticles, water treatment
Seyed Mostafa Mir , Esmaeil Samadian, Sahar Alijanpour , Alireza Khoshbin Khoshnazar , Hamid Haghighatfard, Seyed Hossein Sadeghi,
Volume 10, Issue 5 (9-2016)
Abstract
Background and Objective: The cell division cycle 25 (CDC25)is a familyof highly conserved dual-specificity phosphatases that activate cyclin-dependent kinase complexes. These complexes are the main cell cycle regulators. Mammalian cells ,exposure to DNA damaging radiations such as ionizing radiation and ultraviolet light, prevent cell cycle progression by activation of checkpoint pathways and lead to cell death.
Methods: In this study, mice were exposed to different doses of ionizing radiation. Their total cellular protein was extracted from the bone marrow. After determining and matching the protein concentrations, CDC25A phosphatase levels were measured by western blotting.
Results: The results showed that exposure to different doses of ionizing radiation in vivo significantly increased the expression of CDC25A compared to control group (P <0.05).
Conclusion: Exposure to ionizing radiation increases the expression of CDC25A phosphatase, which increases the possibility of tumorigenesis in that area by increasing bone marrow cell proliferation.
Keywords: Cell Cycle, CDC25A, Ionizing Radiation, Cyclin-Dependent Kinase.
Seyed Mostafa Mir, Esmaeil Samadian, Seyed Hossein Sadeghi, Alireza Khoshbin Khoshnazar ,
Volume 11, Issue 2 (3-2017)
Abstract
ABSTRACT
Background and Objectives: Exposure to ionizing radiation in modern societies is inevitable and can cause a variety of adverse health effects such as cancer and birth defects. Therefore, a reliable, repeatable and sensitive method is required for evaluation of radiation exposure. The aim of this study was to determine the amount of histone H2AX phosphorylation as an indicator of radiation exposure to evaluate the rate of double-strand DNA breakage in irradiated mice.
Methods: In this study, 15 mice were exposed to different doses of ionizing radiation. After extraction of total protein from bone marrow cells, γH2AX protein was measured by western blotting. Data analysis was performed using ANOVA, Tukey's post hoc test, and the Pearson's correlation test.
Results: The amount of γH2AX protein in the exposed groups increased significantly compared to the control group (P<0.05).
Conclusion: The results of this study indicate that exposure to ionizing radiation increases the amount of γH2AX protein in bone marrow cells during the early hours. The protein can be used as a biomarker for monitoring of acute radiation or suspected local radiation exposure.
Keywords: γH2AX Protein, Ionizing Radiation, Mouse.
Iffat Jamal, Shuchismita ., Vijayanand Choudhary,
Volume 16, Issue 6 (11-2022)
Abstract
Hypocellular acute myeloid leukemia (AML) is an infrequent and challenging entity, and superinfection with coronavirus disease 2019 (COVID-19) could further complicate its diagnosis and management. It is characterized by low bone marrow cellularity, prominent cytopenias, and in many cases, clinically simulate aplastic anemia and hypoplastic myelodysplastic syndrome. We report a case of hypocellular AML-M2 in a 65-year-old male who was found to be COVID-19-positive. The cause of hypoplasia of bone marrow in such cases is still ambiguous and could be due to infiltration by blasts or co-infections. The cause of hypoplasia must be determined for proper management, which requires analysis of more such cases.
