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Simultaneous Effect of Resistance Training and Portulace Oleraceal Supplementation on Some Biochemical Markers of Bone Dynamics in Women with Type II Diabetes
Shokufe Ziadloo , Parvin Farzanegi , Masoumeh Habibian ,
Volume 10, Issue 3 (5-2016)
Abstract

ABSTRACT

       Background and Objective: Osteoporosis is one of the complications of diabetes. The aim of this study was to determine the impact of resistance training along with Portulaca oleracea supplementation on OPG and NFκB levels (bone markers) in women with type II diabetes.

       Methods: Overall, 28 women with type II diabetes (44 to 60 years old) were randomly and equally assigned into four groups (supplement, training, training-supplement and control). An eight-week resistance training program (three one-hour sessions per week with one repetition maximum) was performed using three types of bands with different resistances, at 40-50% intensity and 50-70% maximum heart rate. P. oleracea seeds were supplemented daily (7.5 grams mixed in yogurt) for eight weeks. The data was analyzed using descriptive statistics, paired t-test and ANOVA.

       Results: After 8 weeks, OPG and NFκB levels in the three groups of supplement, training and training-supplement increased and decreased, respectively. The highest change in both variables was observed in the training-supplement group. Moreover, the level of these two variables in the training-supplement group had significant difference with the controls and other groups (P=0.000).

       Conclusion: As a non-pharmacological therapeutic approach, the regular resistance training and P. oleracea supplementation can increase bone formation markers and reduce bone resorption in women with type II diabetes.

  


Effect of Four Weeks Plyometric Training with and without Blood Flow Restriction on Serum Bone Formation and Degeneration Markers in Inactive Girls
Fatemeh Fakhri, Abdolhamid Habibi, Mohsen Ghanbarzadeh, Rohollah Ranjbar,
Volume 14, Issue 3 (5-2020)
Abstract
Background and Objectives: It has been shown that low intensity physical activity rarely increases bone density or renewal. Therefore, the purpose of this study was to investigate effects of four weeks of plyometric training with and without vascular occlusion on serum levels of bone‌ alkaline phosphatase (BALP) and C-terminal telopeptide of type I collagen (CTX), as markers of bone formation and bone degeneration in inactive girls.
          Methods: This was a semi-experimental study with a pretest-posttest design. The study population consisted 36 inactive female students aged 23.84±1.096 years with a mean body mass index of 22.59±0.52 kg/m2 who were randomly divided into a plyometric training group without blood flow restriction, a plyometric training group with blood flow restriction and a control group. The experimental groups performed four weeks of plyometric training (three sessions per week), while the control group did not perform any exercise. Blood samples were obtained 48 hours before the first training session and 48 hours after the last training session. Measurement of BALP and CTX was carried out using commercial enzyme-linked immunosorbent assay kits. Collected data were analyzed using t-test and one-way analysis of variance. All statistical analyses were performed using SPSS software (version 23) and at significance level of ≤ 0.05.
          Results: The level of BALP was significantly higher in the low intensity exercise with blood flow restriction group compared to the control group (P=0.005) and the low intensity exercise group without blood flow restriction (P=0.003). The BALP/CTX ratio, as marker of bone metabolism, increased significantly following low intensity exercise with blood flow restriction compared with the other groups (P<0.05). However, low intensity exercise without blood flow restriction induced no significant change in the studied indices.
          Conclusion: Plyometric training with blood flow restriction could be as effective as high intensity training for improving bone metabolism and turnover, particularly in inactive individuals.

Correlation between platelet counts, MPV, PDW, PCT and age in acute ischemic stroke patients
Ebrahim Mohammed Abed Ahamid Ahmed, Babker Ahmed Mohamed , Bakri Yousf Mohamed Nour, Babiker Saad Almugadam ,
Volume 18, Issue 4 (7-2024)
Abstract
Background: Acute ischemic stroke occurs when blood clots obstruct blood vessels within the brain. Platelets (Plts) are integral to the pathophysiology of stroke. This research aimed to explore the relationship between Plt quality and Plt indices in the context of acute ischemic stroke.
Methods: This cross-sectional investigation involved 100 patients diagnosed with acute ischemic stroke at Kosti Teaching Hospital and Alyammama Hospitals. The diagnosis was confirmed using brain CT imaging and electrocardiography (ECG). Blood samples were collected in EDTA-containing tubes within 24 hours following the commencement of treatment and were subsequently analyzed for Plt count, mean Plt volume (MPV), Plt distribution width (PDW), and plateletcrit (PCT) utilizing a hematological analyzer. Data were analyzed using GraphPad Prism software.
Results: Platelet counts negatively correlated with PDW [r=-0.074, P=0.459; R=-0.023, P=0.815], MPV [r=-0.130, P=0.194; R=-0.081, P=0.417], and diastolic blood pressure [r= -0.023, P=0.818; R= -0.024, P=0.805]; and positively correlated with PCT [r= 0.103, P=0.308; R=0.143, P=0.155] and diastolic blood pressure [r=0.022, P=0.823; R= 0.008, P=0.932]. Moreover, PDW positively correlated with systolic blood pressure [r=0.105, P=0.298; R= 0.147, P=0.148] and diastolic blood pressure [r=0.146, P=0.145; R=0.173, P=0.084]. Based on Spearman but not Pearson correlation, PDW showed a negative correlation with PCT [r=-0.005, P=0.959; R=0.010, P=0.929].
Conclusion: The study shows a correlation between Plt count and indices in ischemic stroke patients. The research also presented evidence concerning the relationship between diastolic and systolic blood pressure and Plt counts and indices.
 

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