Thu, May 29, 2025
Shalaleh Ganji1 
, Iraj Mobedi2 , Azim Rezamand1 , Farshid Ardabili3 , Pooya Yari4 , Majid Khanmohammadi5
, Iraj Mobedi2 , Azim Rezamand1 , Farshid Ardabili3 , Pooya Yari4 , Majid Khanmohammadi5
1- Department of Pediatric, Children’s Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
2- Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical sciences, Tehran, Iran
3- Department of Biology, Faculty of Sciences, University of Maragheh, Maragheh, Iran
4- Department of Medical Biotechnology, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
5- Department of Laboratory Sciences, Mara.C., Islamic Azad University, Marand, Iran ,majid593@gmail.com
2- Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical sciences, Tehran, Iran
3- Department of Biology, Faculty of Sciences, University of Maragheh, Maragheh, Iran
4- Department of Medical Biotechnology, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
5- Department of Laboratory Sciences, Mara.C., Islamic Azad University, Marand, Iran ,
Abstract: (393 Views)
Background and objectives: Enterobius vermicularis is the most important intestinal parasite in children worldwide. When this parasite migrates unexpectedly, the larvae move out of the intestine and enter organs such as the appendix and can cause health risks.
Case report: An 8-year-old boy was admitted to the oncology clinic of Tabriz Children’s Hospital complaining of fever of 39-40°C with abdominal pain, cramps, loss of appetite, weakness and fatigue associated with cervical lymphadenopathy, hepatomegaly, axillary mass, abdominal upper thigh, maculopapular rashes and tiny petechiae on the chest and abdomen.
Results: On CT examination of the chest, moderate mediastinal and mesenteric lymphadenopathy was noted. The patient was hospitalized with a definitive diagnosis of acute lymphoblastic leukemia (ALL). On the seventh day of hospitalization, the patient developed additive colic pain (contraction and cramping) around the umbilicus and concomitantly developed pain downward and rightward into the abdomen. Based on the clinical findings, the patient was thought to have acute appendicitis. Pathological examinations showed that E. vermicularis was the cause of the appendicitis.
Conclusion: The results of this study indicate that this parasite may be associated with inflammation of the appendix in patients with acute lymphoblastic leukemia. A screening program is still required in patients with immunodeficiency or those taking immunosuppressive drugs.
Case report: An 8-year-old boy was admitted to the oncology clinic of Tabriz Children’s Hospital complaining of fever of 39-40°C with abdominal pain, cramps, loss of appetite, weakness and fatigue associated with cervical lymphadenopathy, hepatomegaly, axillary mass, abdominal upper thigh, maculopapular rashes and tiny petechiae on the chest and abdomen.
Results: On CT examination of the chest, moderate mediastinal and mesenteric lymphadenopathy was noted. The patient was hospitalized with a definitive diagnosis of acute lymphoblastic leukemia (ALL). On the seventh day of hospitalization, the patient developed additive colic pain (contraction and cramping) around the umbilicus and concomitantly developed pain downward and rightward into the abdomen. Based on the clinical findings, the patient was thought to have acute appendicitis. Pathological examinations showed that E. vermicularis was the cause of the appendicitis.
Conclusion: The results of this study indicate that this parasite may be associated with inflammation of the appendix in patients with acute lymphoblastic leukemia. A screening program is still required in patients with immunodeficiency or those taking immunosuppressive drugs.
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